多糖铁复合物_NIFEREX-150_抗坏血酸钙(琥珀酸)COMPLEX说明书

  [caption id="attachment_38866" align="alignleft" width="300"] NIFEREX-150(多糖铁复合物/抗坏血酸钙/苏糖酸钙/琥珀酸)[/caption] 药店国别： 产地国家：英国 处 方 药：是 所属类别：150毫克/胶囊 90胶囊/瓶 包装规格：150毫克/胶囊 90胶囊/瓶 计价单位：瓶 生产厂家中文参考译名:许瓦兹制药 生产厂家英文名:Schwarz Pharma 原产地英文商品名:NIFEREX-150 150mg/Capsule 90Capsules/bottle 原产地英文药品名:IRON ASPARTO GLYCINATE&POLYSACCHARIDE COMPLEX/ASCORBATE 中文参考商品译名:力蜚能-150 150毫克/胶囊 90胶囊/瓶 中文参考药品译名:多糖铁复合物/抗坏血酸钙/苏糖酸钙/琥珀酸 简介： 部份中文多糖铁复合物处方资料(仅供参) 【商品名】力蜚能 【通用名】多糖铁复合物胶囊 【英文名】Polysaccharide-Iron　Complex　Capsules 【性状】本品为硬胶囊，内容物为棕黑色微丸，溶于水形成深棕色溶液，无味、无臭 【药理作用】本品是一种铁元素含量高达46%的低分子量多糖铁复合物。作为铁元素补充剂，可迅速提高血铁水平与升高血红蛋白。大鼠口服本品的LD50大于2800mgFe/kg。大鼠和狗的长期毒性试验证明，每天摄入本品250mgFe/kg，连续使用三个月，未见不良反应。动物试验未发现本品有致畸、致癌和致突变作用。 【药代动力学】本品是铁和多糖合成的复合物，以完整的分子形式存在，在消化道中能以分子形式被吸收。经核素标记示踪试验证实其吸收率不低于硫酸亚铁，且吸收率不受胃酸减少、食物成分的影响，有极高的生物利用度。 【适应症/功效】用于治疗单纯性缺铁性贫血。 【用法用量】成人每日一次，每次口服1~2粒;儿童需在医生的指导下使用 【不良反应/副作用】极少出现胃肠刺激或便秘 【禁忌】血色素沉着症及含铁血黄素沉着症禁用此药 【注意事项】本品安全性好，安全系数是普通铁剂的13倍以上。多糖铁复合物分子通过肠黏膜吸收阀调节血药浓度，不会导致铁中毒。6岁以下儿童意外服用含铁药品过量可导致致命性中毒，如意外过量，请有经验的医生立即处理;请将本品置于儿童接触不到的地方保存 孕妇及哺乳期妇女用药：对于治疗孕产妇缺铁性贫血，其优越性尤为突出 老年患者用药：无影响 药物相互作用：制酸剂及四环素类药物抑制其吸收 【贮藏】室温(15℃-30℃)贮存 【有效期】三年 【生产企业】德国许瓦兹制药有限公司 【临床研究】国内王耀莉等用多糖铁复合物胶囊(每粒胶囊含铁150mg)治疗缺铁性贫血患儿24例。按患儿年龄和体重，每天剂量为15-150mg，分1-2次服用，持续4或6周。治疗后总有效率为96%，RBC、Hb、红细胞压积(Hct)、血清铁、血清铁饱和度均较治疗前明显上升(P<0.01)。网织红细胞数也上升(P<0.05)。不良反应主要表现为恶心，但不影响治疗。 国内甄学慧等将妊娠合并缺铁性贫血的妇女随机分为实验组(口服力蜚能150mg，bid)和对照组(口服硫酸亚铁0.3g，tid)。治疗4周后复查RBC、Hb、Hct、网织红细胞、血清铁及转铁蛋白。治疗组有效率为90.3%，对照组有效率为84.8%，差异显著。力蜚能治疗19例孕妇贫血，PIC150mg，po，bid，治疗4周后。其Hb、RBC均明显升高。耐受性好。 Niferex Generic Name: Iron What is Niferex? Niferex is an iron supplement to treat or prevent iron deficiency. What is the most important information I should know about Niferex? Keep out of reach of children. Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children <6 years old. In case of accidental overdose, call your doctor or a poison control center immediately. Niferex may cause black stools, constipation, or diarrhea, which is usually transient and self-limiting. Who should not take Niferex? People with hemochromatosis or a family history of this condition should speak with their doctor before taking iron supplements. What should I tell my doctor before I take the first dose of Niferex? Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Niferex. Also, talk to your doctor about your complete medical history, including a history of hemochromatosis. What is the usual dosage? The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval. Adults: 1 or 2 capsule twice daily. Children ≥6 years: 1 capsule daily. How should I take Niferex? Niferex is best absorbed on an empty stomach; however, occasional stomach upset such as nausea may be minimized by taking Niferex with meals. What should I avoid while taking Niferex? Speak with your doctor or pharmacist about any food or drugs you should avoid while taking Niferex. What are possible food and drug interactions associated with Niferex? If Niferex is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Ask your doctor or pharmacist if iron interacts with any other medications you may be taking. What are the possible side effects of Niferex? Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug. Side effects may include: black stools, constipation, diarrhea, nausea Can I receive Niferex if I am pregnant or breastfeeding? The effects of Niferex during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding. What should I do if I miss a dose of Niferex? If you miss a dose of Niferex, take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not double the dose. If you are unsure, ask your doctor or pharmacist for advice. How should I store Niferex? Store at room temperature. Avoid excessive heat or freezing.