处方药：是

所属类别： 5毫克/片 20片/盒

包装规格： 5毫克/片 20片/盒

计价单位：盒

生产厂家英文名：Shionogi

原产地英文商品名：OXYCONTIN Tablets（オキシコンチン錠）5MG 20Tabs/box

原产地英文药品名：Oxycodone Hydrochloride Hydrate

中文参考商品译名：OXYCONTIN（オキシコンチン錠）5毫克/片 20片/盒

中文参考药品译名：盐酸羟考酮

简介：

部份中文盐酸羟考酮处方资料（仅供参考）

英文名：Oxycodone Hydrochloride Hydrate

商标名：oxycontin

生产商：盐野义制药オキシコンチン錠5mg／オキシコンチン錠10mg／オキシコンチン錠20mg／オキシコンチン錠40mg

药品介绍：药效分类治疗癌症的止痛剂

批准日期：2003年6月

欧文商标名：OXINORM

一般的名称：オキシコドン塩酸塩水和物（JAN）［日局］Oxycodone Hydrochloride Hydrate

化学名：(5R)-4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one monohydrochloride trihydrate

分子式：C18H21NO4・HCl・3H2O

分子量：405.87化学

性状：白色的结晶体。水，甲醇或醋酸(100)容易溶化，乙醇(95)稍不容易溶化，不易溶于无水醋酸。因光而变化。

药理作用：镇痛作用对于镇痛作用研究了吗啡硫酸盐。用老鼠的hot plate法、tail pressure法、醋酸抗老化法以及小鼠的tail flick法(两者都会口服)研究的结果，oxcodon的盐酸盐的ed50值为3 ~ 6倍，效力比为3 ~ 5倍。

作用机制：与吗啡一样，可能会通过μ欧片受体表现镇痛作用。

适应症：从中等带高度疼痛的各种癌症

用法与用量：通常成年人每日服用10 ~ 80毫克盐酸盐(无水物质)，每次分两次服用。另外，根据症状适当增减。

包装：片5毫克

英文版说明书：

OXYCONTIN Tablets 5mg（オキシコンチン錠5mg）Brand name : OXYCONTIN Tablets 5mg　Active ingredient: Oxycodone hydrochloride hydrate　Dosage form: pale orange tablet, diameter: 7.1 mm, thickness: 3.3 mm　Print on wrapping: (Face) オキシコンチン 5mg, (Back) オキシコンチン 5mg 913 5Effects of this medicineThis medicine acts on opioid receptors in the central nervous system, thereby relieving pain.It is usually used as an analgesic for various types of cancer accompanied with moderate to severe pain.Before using this medicine, be sure to tell your doctor and pharmacistIf you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.If you have respiratory function disorder, bronchial asthma, heart failure, a history of convulsions, paralytic ileus, acute alcoholic poisoning, hemorrhagic colitis or bacterial diarrhea.If you are pregnant or breastfeeding.If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)Dosing schedule (How to take this medicine)Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>In general, for adults, take 1 to 8 tablets [5 to 40 mg as oxycodone hydrochloride (anhydride)] at a time, twice a day (every 12 hours). The dosage may be adjusted according to your symptoms. In the beginning, take 1 or 2 tablets (5 or 10 mg) at a time, twice a day (every 12 hours). If you have been treated with any other analgesic agents, the dosage of this medicine is properly decided with attention to adverse reactions in consideration of the dosage of other agents and the analgesic duration. Furthermore, the dosage is adjusted to provide the appropriate analgesic effect and to minimize the adverse reactions. Strictly follow the instructions.This medicine is not for use to treat pain that you only have once in a while (as needed).If you still have a pain or feel very sleepy, consult with your doctor.Swallow whole of a tablet without chewing. Do not split or crush a tablet.If you miss a dose, take it as soon as you remember and continue your regular dosing schedule. You should never take two doses at one time.If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.Do not stop taking this medicine unless your doctor instructs you to do so. Sudden discontinuation of taking this medicine may cause adverse events.Precautions while taking this medicineSince this medicine may cause drowsiness or dizziness, avoid driving a car or operating dangerous machinery.Alcohol may enhance the effects or the adverse reactions of this medicine.If you are breastfeeding, avoid breastfeeding while taking this medicine.You may find an object in the shape of a tablet in your stool, however, there is no need to worry about it because this object is an empty shell remaining after the ingredients of this medicine are melted away.Possible adverse reactions to this medicineThe most commonly reported adverse reactions include drowsiness, constipation, nausea, vomiting, loss of appetite, dizziness, itch, somnolence, rash and hives. If any of these symptoms occur, consult with your doctor or pharmacist.The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.facial pallor, breathlessness, swelling around eyes and/or mouth (lips) [shock, anaphylaxis]desire for the medicine even when taking the medicine is not needed [dependence]breathlessness, shortness of breath [depressed respiration]disoriented, speaking in tongues, feeling as if the thing which is not in fact were visible or audible [confusion, delirium]constipation, feeling of fullness in abdomen, severe pain in abdomen [paralytic ileus, toxic megacolon]The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.Storage conditions and other informationKeep the medicine out of the reach of infants and children. Store it at room temperature (1 to 30 degrees Celsius) away from direct sunlight and moisture.Do not give the medicine to anyone else.Return the remainder or the medicine which is no longer needed to your hospital or pharmacist.Shionogi & Co., Ltd. InternalRevised: 6/2015The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.